Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Such claims are unlikely to go away, though. John R. Christy, an atmospheric scientist at the University of Alabama in Huntsville who is known for his skepticism about the seriousness of global warming, pointed out in an interview that 2014 had surpassed the other record-warm years by only a few hundredths of a degree, well within the error margin of global temperature measurements. “Since the end of the 20th century, the temperature hasn’t done much,” Dr. Christy said. “It’s on this kind of warmish plateau.”
Some people remain attached to a theory that can be described as resource scarcity. At its heart this theory suggests that resource development follows a linear pattern in which low-cost resources are developed first, meaning that most if not all future development must be more costly. Unfortunately the history of the industry does not support this view. If anything the experience of the past few decades suggests that the opposite is true.
Trends and targets in antiviral phototherapy
With the release of his book Conscious Capitalism, Whole Foods (WFM, Fortune 500) CEO John Mackey got business leaders thinking about a compelling idea: Companies work best when they create value for all their stakeholders -- not just investors. According to Mackey, key stakeholders include customers, employees, suppliers, society, and the environment. Highlighting companies like Costco, Southwest Airlines (LUV,Fortune 500), and Google (GOOG, Fortune 500), Mackey demonstrates that thinking about more than just the bottom line builds stronger and more efficient businesses.
In P2P lending, borrowers are matched with investors, who are encouraged to put their money into the loans due to higher returns than they could get at state banks.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
8. The 2012 Ig Nobel Fluid Dynamics Prize
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
Still, the optimistic view is that several roadblocks to recovery -- an over-indebted consumer, a moribund housing market and shellshocked banks -- are no longer holding back hiring. Barring an unforeseen shock to the economy, this could mean 2013 will be another year of slow but steady growth.[qh]
The BFC's news has been met with support from people on social media, who have applauded the designers choosing to forgo the use of animal fur.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
4. No talking during the game, wait for half-time or end of the game.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Release date: Spring 2015
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
According to the country's film regulator, China's box office sales have boosted a whopping 48.7 percent in the last year alone.
Then there were these cautionary tales, where a candidate
'He does smoke cigarettes, he smokes many, many cigarettes.
Influenza neuraminidase: A druggable target for natural products
"He (Premier Wen) underlined that China effectively countered the severe impact of the global financial crisis and has maintained steady and fast economic development. This allowed China to become the second-largest economy, almost doubling its GDP in five years."
Upon downloading WeChat, users are prompted to register either using their QQ accounts or their cell phone numbers. The application then helps users populate their contact lists using existing entries in their cell phone address books. To communicate, users can upload any photo or video on their device, take new ones, or press a button to save a voice message that is transferred almost instantaneously. Voice messages are played back with short beeps at the end to imitate the feeling of instant connection, similar to a two-way radio.
But most overseas islands are sold as freehold properties.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
China is now home to over 80,000 trade markets and total retail sales of consumer goods would reach 30 trillion yuan this year with consumption contributing to about 60 percent of total GDP growth, Gao said.
The role of biosensors in the detection of emerging infectious diseases
The show airs on CBS December 4.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
但经济学家总体上预计，一旦飓风造成的失真消失，前段时间的趋势就有望恢复并延续。接受《华尔街日报》最新月度调查的45位经济学家预计，到明年6月，失业率将降至7.8%，2013年年底将降至7.5%。部分经济学家说，就业增长可能会摆脱现在的缓慢速度而加快。信安环球投资有限公司(Principal Global Investors)经济学家鲍尔(Bob Baur)说，我觉得到时候企业将必须招人。[qh]
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Deadpool will release on February 12, 2016 and it looks like it's going to be a hilarious movie. Oh yes, there's going to be plenty of action and killing as well.
New Year comes but once a year. But when it comes it brings good cheer.新年一年只有一次，但每次来临都带来喜悦。
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Did you write The Lego Batman Movie off as kids-only? Biggest mistake ever. This movie is a witty feat of hilarity, full of dry humor and moments of comedy gold. Basically, if you like Will Arnett in Arrested Development, you will like this.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
The gig economy
Inhibition of SARS coronavirus helicase by bismuth complexes
Lighting is key when it comes to getting work done. Instead of investing in your typical, boring college dorm room desk lamp, pick something with a prettier design. Check out vintage stores for one-of-a-kind table lamps or keep it cheap with the Tiffany Table Lamp, $99.99, at Target.com.
Sliced into eight pieces, the pizza works out to $250 per slice, meaning it costs roughly $50 per bite.
The ranking is in part based on how successful alumni have been in their careers, as reflected in the salary data.
瑞士洛桑国际管理发展学院(IMD)和西班牙Iese商学院(Iese Business School)稳坐英国《金融时报》两份高管教育榜单榜首。英国《金融时报》2017年高管教育排行榜开放招生课程和定制课程两份排名的头两名，均由这两所学校包揽。
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
开发商：Dontnod Entertainment、Square Enix
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
After an investigation, Rongchang police arrested Zhou on April 29 for endangering public security, according to the Chongqing Morning Post.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
OUTDOOR SPACE: Steps down from the patio is a walled garden with a lawn and a fountain. The property is 0.10 acre.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Some of them still give high return to their shareholders. China Merchants Bank is generous; its dividend reached 30.16% of its net profits.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
With the right tools in place, you’ll find yourself more productive and efficient.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
至于英国，官方虚构数据同样盛行。英国国家统计局(Office For National Statistics)周二公布，以由来已久的零售价格指数(RPI)衡量，去年12月英国通胀率上升至4.1%。该数字纯属胡扯，英国国家统计局对此心知肚明。该机构告诉人们RPI“没有达到规定标准”，不能作为合格的通胀指标，但自2012年以来该机构一直拒绝采取措施来改善该指标并使之贴近3%的整体通胀率。
Anti-dumping cases were much easier to bring in the US than in the EU where companies first had to pass a public interest test.
Edgar Wright’s Baby Driver is one of the most entertaining thrill rides of this year, this decade. This century.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
The Bulls get the Kings' pick if it falls outside the top 10, so it's better for the Kings to be a bottom-10 team than to just miss the playoffs in terms of team-building.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Gisele, 37, came in second place, having earned $17.5 million, marking the first year she has not headed up the line-up since 2002.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
“…called the interviewer by the wrong name.”
The TV drama is not based on a novel but the story of a real businesswoman Zhou Ying. Born in the Qing Dynasty (1644-1911), Zhou was the richest female entrepreneur in Shaanxi province at that time.
Columbus Day became a U.S. holiday in 1971. It is generally observed by banks, state government offices, the Postal Service and federal agencies. The bond markets are closed for the holiday, but many businesses and stock exchanges remain open.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
On Thursday it published its mascot for 2016, the Year of the Monkey, and instantly it became a hit on the Internet; unfortunately some people deemed it "very ugly".
戈尔迪·霍恩（Goldie Hawn）曾因影片《仙人掌花》（Cactus Flower）获最佳女配角奖，她的奖杯坐落在一个非常富有禅宗气息的地方——她的“印度房间”，她常在这里冥想。她的小金人并不是唯一一个和主人有共鸣的奖杯，罗素-克洛（Russell Crowe）曾在影片《角斗士》（Gladiator）中身着罗马战士裙装，扮演了一个威猛、极具感情和个性的古罗马战士--司令官马克西姆斯，他的奖杯放在鸡舍中，因为克洛相信小金人能够保佑母鸡下出更大的鸡蛋。
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
The values of the citizenry are a democracy’s most important asset.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
The dumbest 'smart' objects of 2016
Successful CEOs tend to follow a structured, daily schedule of rising early, exercising, having snacks on hand for fuel and socializing many evenings of the week.
Two-thirds of this year’s deals are trading above their issue price. On average, 2017’s class of US IPOs have risen in value by about double the S&P 500, at 20 per cent, according to Renaissance Capital, which runs IPO-focused exchange traded funds.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Google and Amazon rank second and third respectively.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
For co-founder Harper, a top priority for the next 12 months is shoring up Bigcommerce’s internal technical talent and creating services that help merchants build closer customer relationships. One example is offering data that helps store managers track “abandoned carts” and offer deals that help turn browsers into buyers. This can help merchants quickly add 15% to their monthly sales, he said.
On Turkey, which recently shot down a Russian warplane, Putin said he sees no possibility of overcoming the strained ties with the current Turkish leadership. He said he was shocked to see that Turkey hadn't tried to explain its action but turned to help from NATO instead.
To be sure, that excitement can certainly lead to unrealistic declarations from those in the community. Some bitcoin developers and investors proclaim that within five years, all the major banks will be accepting bitcoin. That’s a stretch, acknowledges Peter Smith, COO of the bitcoin wallet Blockchain (not to be confused with the actual bitcoin block chain). “I hear a lot of predictions about how soon the whole world will be using bitcoin, and most of the time, those are unrealistic,” he says. “What we’re trying to do as an ecosystem is incredibly audacious, so it’s going to take a lot of time.”
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
TAXES: Approximately $18,036 a year
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
节目31 京剧《迎来春色换人间》，于魁智 托马斯（孔子学院学员）
"People should just never walk away and leave their animals," Ms Lewis said. "Everyone has a legal obligation to look after animals in their care."
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A Larger Profile
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Rouslan Krechetnikov和Hans Mayer对液体的溅出现象进行了研究。他们考察的课题是：人们在端着咖啡杯走动时咖啡的溅出情况，给你个提示吧，在你走到第七步至第十步之间，咖啡最容易溅出。
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Extreme heat blanketed Alaska and much of the western United States last year. Records were set across large areas of every inhabited continent. And the ocean surface was unusually warm virtually everywhere except near Antarctica, the scientists said, providing the energy that fueled damaging Pacific storms.
In the foreseeable future, China will see the boom of enterprises in tertiary industry. Related majors, including law, journalism and communication, and management, are expected to play a bigger role, according to the report.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
They say that it is especially risky to use the same password for entertainment sites as for email and social networking accounts.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
“We will see a lot of headlines about [emerging market export growth] picking up in the first half of 2017,” says Bhanu Baweja, head of EM cross asset strategy at UBS, who believes EM exports will show year-on-year growth of between 8 and 13 per cent in dollar terms in the first quarter of this year, “a complete postcode away” from the negative numbers currently being reported.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Those quickly sold out, locking out the vast majority of fans in soccer-mad Brazil.
Length-scale dependence of protein hydration-shell density
日前，斯坦福大学商学院(Stanford Graduate School of Business)教授彼得o库迪斯基于这场荷兰危机共同撰写了一篇文章，围绕“个人经验（而非市场信息）决定乐观、悲观以及信贷的获得与否”这种不那么科学的方法给出了现代经验。
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
英国大选就是个教训。民调也不过是戛纳的“外卖餐点”：预测是傻瓜才干的事。一整周，坊间盛传托德?海因斯的女同性恋恋爱故事《卡罗尔》将斩获金棕榈最佳影片奖，或者拉斯洛?杰莱斯László Nemes 处女作《索尔的儿子》Son of Saul将折桂。最后几天，共识则是来自台湾的导演侯孝贤（Hou Hsiao-Hsien）指导的《刺客聂隐娘》（The Assassin）将问鼎大奖。且据英国博彩分析，《龙虾》是个难缠的对手。但是，最终宣布雅克?欧迪亚Jacques Audiard's 《流浪的迪潘》Dheepan获奖时，大家一致惊讶表示：“真的吗？”所有的评论员、影评人小组、内部八卦、数据统计、上帝都知道，只是少有人提及罢了。好吧，这就是生活。
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
My fellow trainer, Sylvia Guinan, made me aware of these rules that a husband has laid out for his wife to follow during the 2014 World Cup.
“Policymakers around the world are cognisant of the impact the Fed decision will have and are worried, which makes us worried,” said Simon Lue-Fong, head of global emerging debt at Pictet Asset Management. “People are saying the decision is priced in but seeing as no one knows exactly what will happen how can that possibly be true.”
Last year was especially striking because global heat records were broken or tied in every month except January and April, researchers said.
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Quanta Computer, ” in October. Samsung is also reported to be working on a 12 to 13-inch tablet, and it seems evident that “these large-size tablets will greatly impact ultrabook demand.” This “iPad Max” will be a defacto laptop with the addition of new cases with integrated keyboards and batteries and could well become a mainstay for high schools and college students who need better content creation tools than thos offers on existing iPads and iPad Minis.