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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

“整个20世纪下半叶,在世界各地,贸易和经济增速都出现了这么大的差异。所有的专业化分工都意味着出口增长快于GDP增长,”威廉姆斯说。
2.听觉矫治专家

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

1."The Little Kicks" in Seinfeld Almost Didn't Happen
badminton;basketball;fencing;Judo;Ping Pang;taekwondo;Tennis;weightlifting;Wrestling;Volleyball;Boxing;Hocky.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Best Companies rank: 61

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

1. Am I taking care of myself? Sometimes we get so wrapped up in taking care of others that we forget to take care of ourselves. It can be so easy to leave ourselves behind.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

On the long voyage to World Cup triumph, Belgium and Uruguay are two icebergs that the favorites would rather avoid. Both nations, despite being underdogs in this year's tournament, have the ability and the nous to upset their bigger and brasher rivals. Yet it's remarkable, given their small size and history as geopolitical doormats, that they remain competitive at all.
在人类的历史上,我们正处于最和平的年代。早在二十世纪四十年代,每10万个人中就有300人直接死于战争。我们可以很欣慰地告诉你今天这个数字少于1。
supervision
ceremony

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

单词embrace 联想记忆:
The ranking is based on data collected from two surveys: one of the participating business schools and the other of alumni who graduated three years ago — the class of 2013.
Even if Asian countries introduced regulation similar to that of thriving ETF markets elsewhere in the world, there are other hurdles. Mr Montanari says, for example, that most products presented to Asian investors relate to equities in their domestic market so the ETFs are not being used to give investors local exposure to foreign markets.
卓越雇主排名:59

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

这位名叫波比·博伊登的小选美冠军穿着一身黑色的连衣裤,带着鬈曲的假发,非常熟练的跳着扭臀舞,向观众们飞吻。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Writing for a Variety Special: Patton Oswalt, “Patton Oswalt: Talking for Clapping”

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

WASHINGTON: Indiahas trimmed its holdings of US government securities to $77.5 billion at the end of October even as the world's largest economyis expanding at a moderate pace.
Comic skit “You’ve Got Trouble”(Sun Tao, Qin Hailu etc)

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 北京冬奥村赛后将变身人才公租房
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

"这个家伙对当前情况作了利弊权衡:他有很大机会从故障电梯逃生,但是如果家庭作业没完成,他会很倒霉。"一名名为Zealshifang的用户调侃道。
今年,竞争最激烈的职位--中国民主同盟中央委员会接待处--有大约10000人参与竞争。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Gunal Youssouf, 23, is a Teach Firster who has joined the UK arm of PwC’s management consultancy graduate scheme. She says the two-year program-me gave her a chance to taste teaching without the cost of studying for a traditional qualification.
3.别理会那些出现在CNN国际频道里、告诉你英国行为规范的打领结的专家。这些家伙通常来历不明,自己住在美国加州,却试图提供一些要么不相干要么过时了的建议。比如说,他们通常会告诉你,英国人喜欢排队;喜欢说对不起,即使有时候并不是他们的错误。而事实上,英国人也喜欢插队,而且还会用咳嗽把排在他们后面的人也吓跑。这取决于天气有多闷热潮湿。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

在成为德国最大贸易伙伴之前,中国是德国在亚洲的最大贸易市场。在过去两年里,德国一直是中国在欧洲最大的贸易伙伴。
单词tunnel 联想记忆:
据中国的官方媒体报道,2017年中国电影票房收入增长了13.5%,而今年仅略有下降。
总体来看,36%的人相信末日论,而63%的人相信是气候变化的结果。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 山寨“华润”安徽霍邱诈骗疑云
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

n. 利益,津贴,保险金,义卖,义演

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

vt. 补给,供
全球性肥胖

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Most remittances ($117 billion) came from the United States, followed by Europe ($115 billion) and the Gulf states ($100 billion).

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

201012/122342.shtml

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Since then, China has been issuing stamps on the theme of the lunar calendar every year to mark the 12 Chinese astrological signs.
鉴于之前许多邦女郎在007电影中如昙花般一现,随后便星途黯淡,玛尔洛和经纪人正努力确保她与众多一流演员合作,正如邦德电影是用来为她的国际演艺生涯铺路一样。
This is the moment hundreds of lovestruck Irish football fans gathered around a blonde French girl and serenaded her - and one admirer even stole a kiss from the woman at the end.
[p?n'demik]

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

“You can choose to spend the time however you like,” he wrote, suggesting people “go travelling, pursue a philanthropic project, spend quality time with family or simply take time out to recharge and refocus”.
enterprise
学员平均年龄:36岁(英语授课项目)
Fidget Spinner
但是Jalava并没有拒绝医生的建议(出于伤情的实际情况考虑,拒绝很困难),而是将这个建议作为自己的期待。他决定试一试,并且真的在植入的手指里放入两千兆字节的数字存储器。他现在只需将指甲剥掉,露出USB插头,即可将手指插入电脑连接。他也可以在任何时候拿掉整个手指,并且借给朋友使用。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

2014年最佳引擎榜单的其他入选者还包括宝马5系豪华轿车和紧凑型雪佛兰科鲁兹(Cruze)所使用的涡轮增压柴油发动机,保时捷Cayman双座运动跑车的水平对置2.7升6缸发动机以及大众汽车捷达紧凑车的1.8升4缸涡轮增压发动机。
5. Women keep rising.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Format: Some 18 courses, including four electives, are spread out over every other weekend in Chicago, with three residential weeks in Chicago, one week in Hong Kong, and one week in London

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

authority

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

各类公司均表示要扩充高级系统分析师队伍。与今年的薪酬水平相比,这一职位的起薪预计会增长5%,达到8.55万美元;大型企业中,金融分析师的起薪将达到8.15万美元,比2010年增长4.8%;经验丰富的行政助理的薪水也将上涨3.1%,达到4.175万美元。
除非查尔斯-奥克利成功控诉纽约老板詹姆斯-多兰,尼克斯2016-17赛季唯一的亮点将是克里斯塔普斯-波尔津吉斯在全明星周末斩获技巧挑战赛冠军。
格温o史蒂芬尼的广告在好几个应用上同时推出,其中就有总部位于硅谷的短信应用Tango。Tango主要通过用户收件箱里的广告赚钱,但它已采用了Swyft的平台,该公司广告和平台副总裁理查德o拉百特表示,这类广告非常契合人们使用Tango的方式。一年前,Tango决定不再卖贴纸了,因为向用户要钱总会带来很多摩擦。拉百特称:“在人们沟通过程中放上一道‘留下买路钱’的大门绝不是我们希望带给用户的体验。”所以,就由Swyft来提供这种广告吧。
I am here to speak on behalf of the starving children around the world whose cries go unheard. 我演讲是为了世界所有忍受饥饿的儿童,而他们的哭泣却无人听见。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

turkey
去年,伊斯兰国激进分子在土耳其驻摩苏尔领事馆扣押了49名土耳其人质,三个多月后才释放他们。人质中包括外交官、军人和儿童。
Compared with an average age of 45, 52-year-old Jack Ma is the oldest among the top 10 IT tycoons.
贝克(Beck),《说再见》(Say Goodbye), Capito

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Nicole Kidman had daughter Sunday Rose at age 40, with her husband, the country singer Keith Urban. 妮可·基德曼40岁时和其丈夫,乡村歌手凯斯·厄本生下女儿桑迪·
The US has overtaken India as the leading user of anti-dumping and other trade defence cases, with China and its steel sector the biggest target, according to research.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

However, others argued that doctors' hands may be forced by an unfair system. "As a patient, I'm more concerned about whether they can cure my illness rather than how many papers they've published," another netizen said.
Some Brexiters and Republicans believe in the ideal of absolutely free markets.
求职市场很艰难并非意味着找到工作是不可能。Challenger说:“你应该更努力地去找工作。”
她表示:“美国宪法第一修正案中对于言论自由的保护仅针对公共实体的违法情况,而哈佛是所私立大学,所以第一修正案根本不适用。”
弗拉德-迪瓦茨令人尴尬的新闻发布会,Vivek Ranadive对巴迪-希尔德的兴趣被透露,以及未能换回选秀权的多余球员。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

5)我支持你:我们都犯过大错误。此时,不要回避,要对对方说一些肯定的话语:“我不是在说你不行。你会度过这个难关的。你不是一个人在战斗。我们将一起解决此事。一切都会没事的。”
塞巴斯蒂安佩恩(Sebastian Payne)
哈佛大学位居榜首,紧随其后的是麻省理工学院和斯坦福大学。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

扎克伯格还协助成立了一个名为FWD.us的游说团体,旨在推动美国的移民和教育改革。
‘The Good Wife’ Once Will (Josh Charles), Alicia’s illicit love interest, died at the end of Season 5, this sexy CBS courtroom drama seemed as if it might droop and wither, but instead, the sixth season steamed with almost madcap energy, mixing Alicia’s newly fledged political campaign, a war of the roses between Alicia’s new firm and her old one, and the legal travails of Cary, her legal partner. Alicia isn’t quite so good anymore, and that makes “The Good Wife” all the better.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

我在世界最知名的公司之一找到了一份工作,对此学校的关系网络起到了重要的作用,鹿特丹管理学院(Rotterdam School of Management)一名毕业生表示,这家公司是学校的一个公司合作伙伴,因此我基本上是在我的邮箱收到工作申请书的。
While the political system will be fixated on preserving stability as new leaders take the helm, reduced economic flexibility could thwart Beijing's intentions to do so.
Landing a superstar like Cousins for pennies on the dollar won't singlehandedly help the Pelicans carve out a larger slice of the sports landscape in New Orleans, but it's an excellent first step.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

In January, Wal-Mart (WMT, Fortune 500) U.S. president And CEO Bill Simon pledged that the world's largest retailer would hire 100,000 veterans over the next five years. In addition, the biggest private employer in the U.S. said it would offer employment to any honorably discharged veteran within his or her first 12 months off active duty.
凡是这家汽车服务公司的忠实员工在效力满10年后,都可获得一份奖励:在佛罗里达州波卡拉顿的一处度假胜地欢度周末(此地距该公司总部仅15分钟车程)。这项福利此后每5年都可以享受一次。
联邦、州和地方政府的裁员速度开始放缓。去年各级政府部门有逾25万人失去工作。今年截至目前,约有两万人找到了工作。经济学家说,美国的债务和赤字问题引发的担忧可能将限制政府支出和投资,但基础设施支出的任何反弹都会创造就业岗位。至少政府带来的拖累会减小。[qh]

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

普华永道中国内地及香港市场负责人林怡仲表示,市场的波动导致了新股审批的节奏的加紧,从而维持资本市场的稳定。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

目前,微博上最红的10位网红共有4000万名粉丝。Papi酱是目前最火的网红之一,她已经签署了一份合同,视频广告费用达到了惊人的340万美元。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

[d?ɑ:]
2011年,她的妈妈梅丽莎(Melissa)报名参加Lifetime频道的真人秀节目《Dance Moms》。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: O2O将会是板材行业的翻身机会吗?
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

n. 生存,幸存者
我预计,将有更多公司培养懂得如何管理网络的领导人——不只是传统的内部员工网,还包括联系更松散的供应商和承包商网络,通过互联网和社交媒体进行远程管理。
8.出租车司机
We will work to ensure that our people have access to equitable and quality education.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

你可能从未想过一根皮带可以与人工智能相结合,但Belty做到了,并使它看起来很时尚。这个belty会让你不自觉就觉得,“为什么我需要这个?”然后你想可能会是,“如果是黑客入侵,他们把它系得很紧我不能呼吸该怎么办?”第一个问题是合理的;第二个问题有些牵强,但如果它让你三思而后买这个产品,这并不是一件坏事。
Will a stable and liquid bitcoin futures market develop

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

adj. 版权的
读:挨批课。上课时赶上老师心情不好,念一段巨长的诗史批评你。这种方法确实是超凡脱俗,不同一般。E张黄色pic-超凡脱俗,不同一般的

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Skin has the thankless job of coating and protecting your whole body, making it your most easily damaged organ. When you burn or rip off a stretch of skin, your main option right now is to graft some back on from elsewhere on your body. But an effective synthetic replacement skin may not be that far off, thanks to research from Stanford scientists.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

该研究还表明,通过实习找工作或许有价值。接受录用通知的实习生的薪酬水平超过那些收到录用通知但拒绝的实习生。那些没有收到录用通知的实习生的薪酬水平更低。这些群体间的薪酬差距在毕业3年后扩大。
To SKN Company in Russia for exploding old Russian ammunition and creating diamonds. Now that's recycling!
单词movement 联想记忆:
根据报告显示,2016年第三季度增长的工作人员需求还包括拥有品牌推广技能的人,很可能要感谢“小型企业”需要为他们的公司在线网站创造一种有凝聚力的一致性的策略。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

愿新年的快乐一年四季常在。
中国社会科学院近日发布的《中国社会心态研究报告(2016)》显示,一线城市居民生活压力较大,不过小城市也未必是宜居地。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

一位毕业生表示:“伦敦商学院拓宽了我的专业视野,开启了国际职业机遇。”他补充称:“在毕业后的3年里,我在美国、加拿大和香港工作过,辗转于公司银行业务、债务资本市场等多个领域。”
Subdivided flats smaller than 100 square feet (9 square meters) can rent for $385 in the Asian city.
HSBC economist Hongbin Qu said the survey pointed to lost momentum in China's manufacturing sector: He expects Beijing to respond with measures to counteract the slowdown.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

除非查尔斯-奥克利成功控诉纽约老板詹姆斯-多兰,尼克斯2016-17赛季唯一的亮点将是克里斯塔普斯-波尔津吉斯在全明星周末斩获技巧挑战赛冠军。
Against: Strong in many categories, but without quite managing to be a front runner in any. Perhaps Timothee Chalamet's performance is its best chance of awards success.
此时可能会有旅客好奇,是否会有一座机场超过备受称赞的樟宜机场呢?

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

9. Meghalaya, India-"Meghalaya won't stay this quiet for long; go before thrill seekers storm the Khasi Hills," advises Lonely Planet. Pictured is Nohkalikai Falls, India's tallest plunge waterfall at 340 meters.
在排行榜19年历史上,这是首次出现由两所院校包揽这两项排名头两名的情况。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Transport Ministry spokesman Xu Chengguang told a news conference that no further signs of life had been found and the chance of finding anyone else alive was "very slim."
Among 36,000 who have reached celebrity status on the Internet, 74 percent are women and 87.8 percent are between 17 to 33 years old, while 89 percent have a college education.
教育部表示:“那些严重破坏考试秩序,损害教育公平公正的人将得到他们应得的惩罚。”

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Andy Murray's US Open victory and Olympic gold medal helped him to become the most searched-for British Olympian.
These contraptions, including a nano-sized car, are so small that they’re invisible to the human eye.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 建材行业供需格局有望继续好转
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

事实上,你要毅然坚决地将工作和找工作划清界限。也就是说,你不能偷偷溜出去接听电话面试。不要浏览找工作的平台。不要用你的工作邮件地址申请和联络。“你不要在工作时看色情照片,同样不要在工作的时候看你的简历,”凯说:“你千万不要。”
After a run with One Direction, Harry Styles could have gone anywhere he wanted.
新画像将取代美国首任财政部长亚历山大·汉密尔顿的画像。自上世纪20年末以来,10美元钞票上一直印有汉密尔顿的画像。新版10美元钞票将在赋予女性选举权的宪法修正案正式通过100周年之际开始发行。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

2017年,全球黄金的产量从上一年的3263吨上升至3268.7吨。这是自2008年以来的最小涨幅。2008年金融危机期间,黄金开采量下降了逾2%。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Hailed as one of the greatest films of all time, Taxi Driver tells the story of a depressed ex-Marine who attempts to assassinate a senator after being rejected by a woman he admires. While the titular taxi driver, Travis Bickle, lives a chaotic life filled with drug dealers and prostitutes, his story was never meant to be an unrealistic fantasy. Rather, it meant to expose the very real warning signs of a would-be gunman.
……又唱又跳,希望能得到工作。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Meanwhile producer prices fell 4.9 per cent year-on-year in February, as expected, compared to a 5.3 per cent fall in January. The drop was the smallest in eight months.
transport

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 土地市场降温有助于调控继续深入
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

维多利亚的秘密内衣秀刚刚拉开华丽巨幕,今年的秀也是有史以来最奢华复杂的一次。
The requirements come from one of two newly issued regulations over the taxi and online ride-hailing services by China's transportation authority. The regulations will take effect in October and November respectively.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

可口可乐正在改组其业务,出售其在美国以及全球的瓶装业务,转而专注于生产其很多饮料使用的浓缩汁,以及研发。这些资产出售将让该公司将更多资源投入创新和收购。
安娜还补充道,在巴西筹办世界杯期间,巴西人民却在遭罪。由于大型建设项目造成交通拥挤,耽误了居住在城市郊区穷人的上下班时间,她认为只有富人才会在世界杯倍感享受。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

达奇斯说:星佳在2012年努力保持势头并进行多元化经营。关于公司的品牌讨论明显减少,产品停产的负面消息不断增长,这使得这家游戏公司在2013年有很多工作要做。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

即将来到的投放是为了纪念南韩2010年沉船事件的第五周年,当时有46位船员死亡。南韩把责任归咎于北韩,并且很快的冻结了一切两韩之间的交易和投资纽带。
Sun Yixiao was on his way up last Tuesday evening after school, when the lift suddenly lurched to a stop.
报告称,打造“机遇之城”的关键是技术创新和均衡发展。
但与其他世界主要国家领导人相比,这薪酬已经是最高了。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

12岁的年纪,大多数的小女孩都还在向父母争取打耳洞的机会,努力适应高中生活,从青少年时代开始为将来做准备。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 长春警方立案调查长生生物
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

“治理空气,现在办法是有的,关键是看下多大决心。”
Inflation for consumers, meanwhile, ticked up slightly to 1.5 per cent, versus a five-year low of 1.4 per cent in November.
老爷车:由于今年在一个海外小岛上发现了一大批尘封50年之久的老爷车,导致现在二战后的老爷车的供给充足,价格也显著下降。收藏家们尤其喜欢Packards、Studebakers、Hudsons、Nashes、Kaisers和Henry J’s等型号的老爷车。更令人吃惊的是这批老爷车的车况都十分良好,能够满足日常使用。(财富中文网)

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

At least two Harvard professors, however, questioned the decision to withdraw the offers. Alan Dershowitz, an emeritus professor at Harvard Law School, told the Guardian that losing admission to Harvard was a "draconian punishment" for "very bad taste jokes that students were sending to each other".
“The Big Short” (Adam McKay)

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

对专业投资者而言,2014年最令人沮丧的一点是,美国经济复苏时断时续。2014年1月,经济领域捷报频传。然而,在短短几周内,一场暴风雪席卷全美,各种经济数据似乎也因此停摆。
科技巨头腾讯创始人马化腾凭借2790亿元的身家位居榜首,阿里巴巴的马云和恒大集团的许家印紧随其后,其个人财富分别为2600亿元和2290亿元。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

脱发和头发变白的原因是相关的,科学家首次确认了对此负有责任的细胞。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

The findings of the US and UK scientists are based on thousands of global temperature measurements taken daily on land and at sea.
Captain America: Civil War will hit theatres May 6, 2016. Who's side are you on?
管理着4亿美元资产的基金公司AIS Group的首席投资长赫梅尔(John Hummel)称,全球所有新原油资源的开采成本都较高。他预计到2015年美国页岩油产量将下降。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Changing minds
The U.S. $10 bill will feature the portrait of a notable U.S. woman by 2020.
同期,巴西和俄罗斯分别减持到2617亿美元和1089亿美元。
['sep?reit]

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

对于其他队伍而言,在球场上拥有良好判断力的德国也是一直非常出色的队伍。意大利也是世界杯上无法忽视的队伍,而拥有罗纳尔多的葡萄牙队将会是一直极具危险性的队伍。拥有众多的大将的比利时队也将成为人们口中津津乐道的黑马队伍。
体积大未必就是好的。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

In response to the incident, Jiedaibao made an announcement on its Sina Weibo on Dec. 1, stressing that the use of nude pictures as collateral for loans constitutes a private deal between users, which the company cannot regulate.
The country has rolled out measures to promote new-energy vehicles, including tax exemptions, subsidies for car purchases and a requirement for government departments to buy more new-energy cars.
3.1 用改革的办法深入推进“三去一降一补”。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

过去10年,全球最具价值品牌100强的品牌价值增长一倍多,增幅达到133%。品牌价值是根据收入和盈利能力等财务指标,结合消费者品牌认知调查计算的。
Overall, St Gallen’s alumni report a 95 per cent satisfaction level, 2 percentage points more than the alumni from London Business School and WHU Beisheim.

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